Mechanism of DNA Replication:General Pattern

• Deoxynucleoside triphosphates

  • dATP, dGTP, dTTP, dCTP

• ORIGIN

  • Recognized by an initiation protein
  • Bacteria: single origin called oriC
  • Eukaryotes: multiple origins

• Bidirectional unwinding

• Termination region (ter)

• Replicon: region replicated from one origin

oriC

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