Cofactors

• Essential Trace Elements: 15 known

  • Iron:
    • henoglobin, myoglobin, cytochrome c
    • cytochrome oxidase, catalase, peroxidase
    • electron carriers: ferredoxin
  • Copper
    • cytochrome oxidase
    • lysyl oxidase: cross-linkages incollagen & elastin
  • Zinc
    • ~100 different enzymes
    • NAD+, NADP+ dehydrogenases
    • DNA & RNA polymerases
    • Carbonic anhydrase
  • Manganese: phosphate transfers
  • Cobalt

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