PPT Slide

Oncogenes that code for transcription factors have mutations that inactivate transcription or that activate transcription

Transcription

Factor

Thyroid

Hormone

Receptor

p65-p50 dimer

I-k B

c-rel has 60% homology with p50

nuclear membrane

Normal

Function

Oncoprotein

Function

Normal

Function

Oncoprotein

Function

NF-kB

NF-kB

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