Preparation for Translation: Charging of the tRNA
Aminoacyl-tRNA Synthetase: enzyme that binds activated amino acid to proper tRNA at 3’ end
- Amino Acid activated by ATP to form Amino Acid-AMP + PPi
- Amino Acid binds to the adenine through the 3’-OH to the carboxyl group of the amino acid.
- Some have proofreading ability