Study Questions - Hardy-Weinberg Equilibrium
1) Define population, gene pool, gene frequency, and genotypic frequency.
2) What two elements describe the genetic structure of a population?
3) Calculate the genotypic and gene frequencies for a population in which the number of AA=100, Aa = 200, and aa = 600. Is this population in HWE? Do the correct staistical test.
4) List the assumptions of the Hardy-Weinberg equilibrium model.
5) If the assumptions of HWE are met, what will happen, and when?
6) Consider this population: AA= 0.4 Aa= 0.2 and aa=0.4. What are the gene frequencies. If the population meets the assumptions of HWE, what will the genotypic frequencies be in the next generation?
7) What genotypic ratio would you expect (in HWE) to see if the gene frequencies at the blood group locus were: A = 0.3, B = 0.2, O = 0.5?
8) If a gene is X-linked, and the frequency in females = 0.2 and the frequency in males = 0.8, what will the frequencies be in the next generation? What will the equilibrium frequencies be?
9) Consider the human A, B, O blood antigen locus. If the frequency of the A allele = 0.3, and the frequency of the B allele = 0.3, and the frequency of the O allele = 0.4, what are the expected genotypic and phenotypic ratios in the population?