BIO 440: Population Genetics and Evolution

Study Questions - Modeling Selection

 

1) Consider this population. Calculate the genotypic frequencies after one generation of selection.

What type of selection is this? How will delta-p change over the course of several generations? Why?

p=0.3 q = 0.7 AA Aa aa  
parental zygotes 0.09 0.42 0.49 = 1.00
prob of survival 0.8 0.8 0.4  
rel. fitness        
         
genotypic frequencies in the reproductive adults        
gene frequencies in the gene pool        
Genotypic frequencies in the F1        

2) Consider this population (yes, it's different):

p=0.3 q = 0.7 AA Aa aa  
parental zygotes 0.09 0.42 0.49 = 1.00
prob of survival 0.6 0.8 0.4  
rel. fitness        
         
genotypic frequencies in the reproductive adults        
gene frequencies in the gene pool        
Genotypic frequencies in the F1        

What will happen over time? Where will p equilibrate?

3) How can the rfequency of an allele affect its selective value? Provide inverse examples.

4) We usually think of selection as directional... in which case the population becomes less variable at that locus. Think of as many mechanisms as you can that invovle seelction maintaining variation at a locus.